small size LDL has bad health effect compared to large size LDL. small LDL seems to trigger the process of atherosclerosis more compared to large LDL. HDL also comes in various sizes and large HDL seems to do a very good job of hauling the cholesterol back to the liver. HDL also has very good anti oxidant effect.
large lipo proteins also may be a clue to longevity. a modest amount of exercise is best way to increase the size of LDL and HDL. transfat promotes smaller size LDL particles thus making transfat more dangerous for your health.
smaller LDL particles are also found in people who have insulin resistance syndrome. LDL particle size is also found to be inversely proportional to total triglycerides.
atherogenesis is the formation of lipid deposits in the arteries, smaller LDL particles and high TG – triglycerides are key factors in the formation of plaque in the lining of the arteries